WHO Classification of Tumours of the Digestive System: Fourth Edition' is an authoritative and concise reference book providing an international standard for oncologists and pathologists. Indispensable as a guide for use in the design of studies monitoring response to therapy and clinical outcome. This book also provides user-friendly algorithmic approaches to the diagnosis of the major tumours of the digestive tract. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include: new ICD-O codes; incidence; age and sex distribution; location; clinical signs and symptoms; pathology; genetics; and predictive factors. This publication has been prepared by more than 100 authors, originating from 22 countries. It contains approximately 700 colour photographs, together with numerous tables, figures and more than 3,700 references.